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The long-acting bronchodilators include tiotropium (Spiriva), salmeterol (Serevent), formoterol (Foradil, Perforomist), arformoterol (Brovana), indacaterol (Arcapta) and aclidinium (Tudorza).

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Acetylcholine is the natural chemical that causes the airway muscles to narrow and contract, and tiotropium eliminates the action of acetylcholine.

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